Purpose Active Ingredient
Muscle relaxer baclofen
Miorel, Kemstro, Lioresal.
Baclofen is an antispastic agent and also a muscle relaxer. Muscle symptoms caused due to multiple sclerosis such as pain, spasm and stiffness can be treated with the help of Baclofen.
An oral medication, Miorel helps in relaxing the skeletal muscles. These are the muscles (also known as striated muscles) that help in the movement of the skeleton. Talking chemically, baclofen is related to gamma-aminobutyric acid (GABA), which is a naturally formed and naturally occurring neurotransmitter in the brain. Nerves communicate with each other through the various neurotransmitters. GABA is released by some nerves and it again reduces the activities of the other nerves. It has been seen that Baclofen, acts like GABA, and plays a role in blocking the activities of nerves within a portion of the brain, which is responsible for relaxation and contraction of the skeletal muscle.
The spinal cord nerves are directly affected by Baclofen and that helps in reducing the number and the intensity of the muscle spasms that are the result of multiple sclerosis or ailments related to the spinal cord. Baclofen is also used in the treatment of skeletal muscles that lead to rigidity, muscle clonus and pain caused from multiple sclerosis. It plays an important role in relieving pain to a great extent and also helps in smoothening muscle movement.
Miorel effective dosage
Miorel can be taken orally. The dose of the medicine is thrice daily at regular intervals of time. Baclofen should be taken as per doctor’s prescription. Do not increase or decrease the dose of the medicine or take it more frequently than recommended by the doctor. The best results of the medicine can be felt only after it has been taken for few weeks. Do not step the intake of Miorel even after you start feeling better. Also, while stopping Baclofen, do consult your doctor. The doctor will recommend as how and when the doses will be reduced.
Baclofen dose for an adult at the starting phase is 5mg, which is to be taken thrice daily. The responses of the doses are monitored, and the dose can be increased step by step every three days and can be increased to a maximum of 80mg per day in many doses.
In case you miss out on a single dose, make sure that you take it as soon as possible if it is within an interval of one hour. In case you remember it much later, just skip the dose and continue with the regular dose. Do not take double doses.
Miorel side effects
Miorel can cause many side effects like increased urinary frequency, confusion, dizziness, low blood pressure, drowsiness, urinary retention, nausea, respiratory depression, headache, vomiting, inability to sleep, seizures, constipation or weakness.
Reduction in brain function might take place if Miorel is used with other medicines that are responsible for lowering the nerve functions. Apart from causing depressing brain function, tricyclic antidepressants (like Sinequan and Elavil) and Baclofen can lead to muscle weakness. Use of monoamine oxidase inhibitors (like Parnate and Nardil) and Baclofen can cause increased depression of the functions in the brain and also cause low blood pressure. Baclofen has the tendency of increasing the blood sugar levels in the body. As a result antidiabetic drugs might need to be given when treatment with Baclofen is started.
The side effects caused by Miorel might affect your thinking and reaction power. Under this medication, be very careful while driving or in doing things that demand lots of attention. Alcohol should also be avoided as it might augment some of the side effects that are caused by the intake of Baclofen. Miorel should not be taken at a time when you require muscle tone. This is to have safe balance and movement for various activities that you carry out. In you are suffering from reduced muscle tone; it might cause great physical harm to you in any situation.
Withdrawal symptoms like hallucinations and seizures are also quite common once you stop taking Miorel after taking it for a long period of time continuously. Therefore you must seek advice from your doctor before you stop taking the medicine suddenly. The dosage of the medicine should be reduced gradually and then stopped.
The effect of Miorel on pregnant woman has still not been studied. If a mother is taking oral Baclofen, it can be detected in the breast milk. However, no data is available for breast milk of mothers who take baclofen intrathecally.
Miorel should be stired within a temperature range of 15°C (59°F) and 30°C (86°F).